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Shrikant Deshpande Selected Research

Neoplasms (Cancer)

12/2021Feasibility of bone marrow sparing volumetric modulated arc therapy to spare active bone marrow in cervical and vaginal cancer patients: a retrospective dosimetric analysis.
5/2021Quantifying and Assessing the Dosimetric Impact of Changing Gas Volumes Throughout the Course of VMAT Radiation Therapy of Upper Gastrointestinal Tumors.
11/2020Design, Synthesis, and Structure-Activity Relationships of Novel Tetrahydroisoquinolino Benzodiazepine Dimer Antitumor Agents and Their Application in Antibody-Drug Conjugates.
10/2020Synthesis and Biological Evaluation of a Carbamate-Containing Tubulysin Antibody-Drug Conjugate.
1/2020Design, synthesis and biological evaluation of phenol-linked uncialamycin antibody-drug conjugates.
1/2019Uncialamycin as a novel payload for antibody drug conjugate (ADC) based targeted cancer therapy.
10/2018A Novel, Fully Human Anti-fucosyl-GM1 Antibody Demonstrates Potent In Vitro and In Vivo Antitumor Activity in Preclinical Models of Small Cell Lung Cancer.
1/2017Structural basis for cancer immunotherapy by the first-in-class checkpoint inhibitor ipilimumab.
7/2014Antibody-drug conjugates: current status and future directions.

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Shrikant Deshpande Research Topics

Disease

9Neoplasms (Cancer)
12/2021 - 07/2014
2Carcinoma (Carcinomatosis)
10/2020 - 10/2009
1Head and Neck Neoplasms (Head and Neck Cancer)
02/2023
1Squamous Cell Carcinoma of Head and Neck
02/2023
1Vaginal Neoplasms (Cancer, Vaginal)
12/2021
1Pancreatic Neoplasms (Pancreatic Cancer)
05/2021
1Gastrointestinal Neoplasms (Gastrointestinal Cancer)
05/2021
1Ovarian Neoplasms (Ovarian Cancer)
10/2020
1Lung Neoplasms (Lung Cancer)
01/2019
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
10/2018
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
11/2017
1Colitis
11/2017
1Melanoma (Melanoma, Malignant)
01/2017
1Dengue (Dengue Fever)
09/2016
1Posterior Uveitis
09/2016
1Macular Degeneration (Age-Related Maculopathy)
09/2016
1Optic Neuritis (Retrobulbar Neuritis)
09/2016
1Renal Cell Carcinoma (Grawitz Tumor)
05/2013

Drug/Important Bio-Agent (IBA)

6Immunoconjugates (Immunoconjugate)IBA
11/2020 - 05/2013
3AntigensIBA
10/2020 - 07/2014
2MesothelinIBA
10/2020 - 01/2019
2Cytotoxins (Cytolysins)IBA
01/2020 - 01/2019
2Monoclonal AntibodiesIBA
01/2017 - 07/2014
1BenzodiazepinesIBA
11/2020
11,2,3,4-tetrahydroisoquinolineIBA
11/2020
1CarbamatesIBA
10/2020
1AntibodiesIBA
10/2020
1Surface Antigens (Surface Antigen)IBA
10/2020
1Peptide Hydrolases (Proteases)FDA Link
10/2020
1serum P-component (CIt)IBA
10/2020
1DipeptidesIBA
10/2020
1uncialamycinIBA
01/2019
1Anti-Bacterial Agents (Antibiotics)IBA
01/2019
1Complement System Proteins (Complement)IBA
10/2018
1Cisplatin (Platino)FDA LinkGeneric
10/2018
1Etoposide (VP 16)FDA LinkGeneric
10/2018
1GangliosidesIBA
10/2018
1Immunoglobulin G (IgG)IBA
10/2018
1ChemokinesIBA
11/2017
1Proteins (Proteins, Gene)FDA Link
11/2017
1CytokinesIBA
11/2017
1IpilimumabIBA
01/2017
1Retinaldehyde (Retinal)IBA
09/2016
1MDX-1203IBA
05/2013
1GoldIBA
10/2009

Therapy/Procedure

3Radiotherapy
02/2023 - 10/2009
3Intensity-Modulated Radiotherapy (Radiotherapy, Intensity Modulated)
12/2021 - 10/2009
2Therapeutics
12/2021 - 01/2019
1Aftercare (After-Treatment)
02/2023
1Chemoradiotherapy
12/2021
1Immunotherapy
01/2017